Excedrin Migraine Headache Relief Caplets provide migraine relief fast, making Excedrin Migraine a recommended OTC treatment for migraines. Excedrin works in 3 ways to relieve migraines: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance pain relief. It combines aspirin and acetaminophen with caffeine. Get migraine relief fast with Excedrin, the headache expert. One bottle of 200 Excedrin Migraine Caplets for Migraine Headache Relief Excedrin Migraine works in 3 ways: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance pain relief effect Pain relievers that provide migraine relief, including migraine headache pain, sensitivity to light and sound, and nausea Excedrin migraine caplets for migraine pain relief combine acetaminophen, aspirin and caffeine Pain medicine delivers a powerful triple action formula with two pain relievers and an amplifier