Inspired by personal experiences, 50/50 is an original story about friendship, love, survival and finding humor in unlikely places. Joseph Gordon-Levitt and Seth Rogen star as best friends whose lives are changed by a cancer diagnosis. 50/50 is the story of a guy's transformative and, yes, sometimes funny journey to health. 50/50 draws its emotional core from writer Will Reiser's own experience with cancer and reminds us that friendship and love, no matter what bizarre turns they take, are the greatest healers.