Drug Delivery Approaches - by Toufigh Gordi & Bret Berner & Heather A E Benson & Michael S Roberts (Hardcover)
Similar Products
Products of same category from the store
All
Product info
<p/><br></br><p><b> Book Synopsis </b></p></br></br>In diesem Werk werden Möglichkeiten der Wirkstoffverabreichung dargestellt, wobei physikalische und pharmakokinetische Modelle zur Erzielung der gewÃ1/4nschten Profile und Ansätze herangezogen werden. Nach einem Ãœberblick Ã1/4ber die Wirkstoffaufnahme und die physiologischen Modelle werden in den Kapiteln Ã1/4ber die oralen Verabreichungswege (die häufigste Form der Verabreichung) die PBPK und verschiedene mögliche Darreichungsformen beschrieben. Bei der systemischen transdermalen Verabreichung ist es notwendig, die Pharmakokinetik der Formulierung und des Wirkstoffs zu verstehen, um die Formulierung von der ersten Konzeption Ã1/4ber die gesamte Entwicklung darauf auszurichten. In weiteren Kapiteln werden die biologischen und praktischen Ansätze bei der pulmonalen und mukosalen Verabreichung besprochen. FÃ1/4r den Fall der Notfallversorgung betrachten die Autoren die Beziehung zwischen parenteralen Infusionsprofilen und PK/PD. In den letzten Kapiteln werden aktuelle Trends dargestellt, darunter virtuelle Experimente zur Verdeutlichung von Mechanismen sowie moderne Ansätze in der Wirkstoffverabreichung und personalisierten Medizin.<br> Das Werk Drug Delivery Approaches: Perspectives from Pharmacokinetics and Pharmacodynamics eignet sich nicht nur perfekt fÃ1/4r Wissenschaftler, Forscher in der Industrie, Doktoranden und Postdoktoranden in den Bereichen der Pharmawissenschaft und Pharmatechnik, sondern verdient auch einen Platz in den BÃ1/4cherregalen von Experten, die sich mit Formulierungen, Pharmakokinetik und klinischer Pharmakologie beschäftigen.<p/><br></br><p><b> From the Back Cover </b></p></br></br><p><b>Explore this comprehensive discussion of the application of physiologically- and physicochemical-based models to guide drug delivery edited by leading experts in the field</b></p> <p><i>Drug Delivery Approaches: Perspectives from Pharmacokinetics and Pharmacodynamics</i> delivers a thorough discussion of drug delivery options to achieve target profiles and approaches as defined by physical and pharmacokinetic models. The book offers an overview of drug absorption and physiological models, chapters on oral delivery routes with a focus on both PBPK and multiple dosage form options. It also provides an explanation of the pharmacokinetics of the formulation of drugs delivered by systemic transdermal routes. <p>The distinguished editors have included practical and accessible resources that address the biological and delivery approaches to pulmonary and mucosal delivery of drugs. Emergency care settings are also described, with explorations of the relationship between parenteral infusion profiles and PK/PD. The future of drug delivery is addressed via discussions of virtual experiments to elucidate mechanisms and approaches to drug delivery and personalized medicine. <p>Readers will also benefit from the inclusion of: <ul><li>A thorough introduction to the utility of mathematical models in drug development and delivery</li> <li>An exploration of the techniques and applications of physiologically based models to drug delivery</li> <li>Discussions of oral delivery and pharmacokinetic models and oral site-directed delivery</li> <li>A review of integrated transdermal delivery and pharmacokinetics in development</li> <li>An examination of virtual experiment methods for integrating pharmacokinetic, pharmacodynamic, and drug delivery mechanisms</li> <li>Alternative endpoints to pharmacokinetics for topical delivery</li></ul> <p>Perfect for researchers, industrial scientists, graduate students, and postdoctoral students in the area of pharmaceutical science and engineering, <i>Drug Delivery Approaches: Perspectives from Pharmacokinetics and Pharmacodynamics</i> will also earn a place in the libraries of formulators, pharmacokineticists, and clinical pharmacologists.<p/><br></br><p><b> About the Author </b></p></br></br><p><b>Bret Berner, PhD, </b> is a pharmaceutical consultant in drug delivery, formulation, and pharmacokinetics. He was formerly Director of Basic Pharmaceutics Research at Ciba-Geigy, Vice President of Development at Cygnus Therapeutics, and Chief Scientific Officer at Depomed. <p><b>Toufigh Gordi, PhD, </b> is a Senior Director of clinical pharmacology at Rigel Pharmaceuticals, with extensive experience in using pharmacokinetic and pharmacodynamic modeling to advance candidate drug molecules from preclinical through late phase confirmatory clinical studies. <p><b>Heather A. E. Benson, PhD, </b>is Associate Professor in Curtin Medical School at Curtin University, Australia where she leads the Skin Delivery Research Group <p><b>Michael S. Roberts, PhD, </b> is Professor of Therapeutics and Pharmaceutical Science at the University of South Australia and Professor of Clinical Pharmacology and Therapeutics at the University of Queensland.
Price History
Price Archive shows prices from various stores, lets you see history and find the cheapest. There is no actual sale on the website. For all support, inquiry and suggestion messages communication@pricearchive.us