HSA/FSA EligibleCVS Health Extended-release Arthritis Pain Reliever Acetaminophen 650 mg 100ct compares to the active ingredient in Tylenol® 8 HR Arthritis Pain. As an extended-release arthritis pain reliever and fever reducer, it offers temporary relief of minor arthritis pain, backache, muscular aches, toothache, premenstrual and menstrual cramps, headache, and the common cold, as well as temporarily reduces fever.